• Thu, Sep 27 2007

Alzheimer’s Disease Coined “Type 3 Diabetes”?

Now scientists at Northwestern University have discovered why brain insulin signaling — crucial for memory formation — would stop working in Alzheimer’s disease. They have shown that a toxic protein found in the brains of individuals with Alzheimer’s removes insulin receptors from nerve cells, rendering those neurons insulin resistant. (The protein, known to attack memory-forming synapses, is called an ADDL for “amyloid ß-derived diffusible ligand.”)

I know I read something similar to this last year. There was preliminary research released stating that there is a direct correlation the way the brain uses, or misuses, insulin and the way that diabetics fight a similar battle.

The most current Northwestern University study is so powerful that they are even coining Alzheimer’s disease as a possible “type 3 diabetes”. What a breakthrough for both diseases this would be! If you want to read the entire article that was derived from a publication released from Northwestern University, check out Science Daily. I warn you, the words are a bit… hard to understand. But you will get the jest. And if you are interested in reading more on Alzheimer’s disease check out a fellow b5 blog Alzheimer’s Notes.

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  • anonymous

    Hi — enjoyed the post.

    But please, please learn where apostrophes go.

    an apostrophe shows possession “bill’s diabetes”
    or they show contraction (“it is” –> it’s )

    but they don’t just go at the end of a word near the s – “diabete’s”

    the plural of cat is cats — not cat’s — that would be possession — the “the cat’s dinner was good”.

    so the plural of disease is diseases, not disease’s.

    Sorry for the grammar lesson, people just seem to be throwing them around at random “oh look! theres an ‘s’ — let’s put an apostrophe in front of it” (the “let’s there is a contraction for “let us”).

    Enjoyed the post!

  • http://www.diabetesnotes.com Kendra James, RN

    Thank you so much for the correction, I must have overlooked the punctuation. After all , I am human as well. Thanks for catching the mistake for me and I am glad you enjoyed the post. :) K

  • Nick Biren

    Sorry, looks like you’re getting hammered by English major’s here, but another correction to your post is the use of the word jest when you should have used the word gist.

    If you’re going to get the jest, you’re looking for the joke. If you’re going to get the gist, you’re going to get the central idea.

    This IS fascinating information, and the first I’ve seen on this issue.

    Thanks for posting it.

  • http://www.diabetesnotes.com Kendra James, RN

    I am no English major :). Science is my forte, that is for sure! Thanks though, the comments are appreciated. Hope you enjoyed the post. I think that even with the grammatical errors, the subject was interesting. I believe that we will see more research in this area in the near future.

  • Bob

    yeah, I remember when I used to correct everyone around me, too. The epiphany that as individuals we are all continually making at least as many mistakes as those we point out in others apparently comes a bit later in life to some.
    Well done to have an experienced RN be so charged up about a breakthrough understanding.

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