Blood Pressure-lowering Hormone Can Shrink Lung Cancer Tumors in Mice
March 19, 2007 by Gloria Gamat
Filed under Diseases & Conditions
Treatment with a blood pressure control hormone – angiotensin-(1-7) – has been found to reduce the lung cancer tumor in mice by 30%, as opposed to a tumor growth of more than double in mice that did not receive the treatment.
Suggesting a new way to treat cancer, these findings have been revealed by scientists at Wake Forest University School of Medicine.
The idea to evaluate the effects of angiotensin-(1-7) on lung cancer came from studies observing that rates of lung cancer were lower in people whose high blood pressure was treated with angiotensin-converting enzyme (ACE) inhibitors. These drugs, which include Capoten® and Lotensin®, increase levels of angiotensin-(1-7) in the bloodstream.
The hormone will be tested in cancer patients by Wake Forest’s Comprehensive Cancer Center.
Find more details from the full report.
