BRIP1 Gene and Breast Cancer
A new mutation in the BRIP1 gene has been found to increase the risk of developing breast cancer almost two-fold. Although the frequency of the genetic variant in the general population is probably not high enough for it to play a large role in many cases of breast cancer, it still helps to understand which genes are involved so the biological pathway to disease can be better understood.
From Medical News Today, a list of currently known genes involved in breast cancer:
- BRIP1 – Doubles breast cancer risk (by age 60)
- BRCA1- Raises risk ten to twentyfold (by age 60)
- BRCA21- Raises risk ten to twentyfold (by age 60)
- TP531- Raises risk ten to twentyfold (by age 60)
- CHEK2 – Raises risk moderately (by age 60)
- ATM – Raises risk moderately (by age 60)
My friend Christina Jones at eBeautyDaily has formed a team to raise money for the Susan G. Komen Foundation. She’d like to raise $1000 which I hope the readers of Genetics and Health can help her achieve. Don’t forget that October is National Breast Cancer Awareness Month.
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