Comments on: Discovering New Genes Using DNA Microarray

By: » 570 Genes for Parkinson’s Disease Genetics and Health

» 570 Genes for Parkinson’s Disease Genetics and Health — Mon, 19 Dec 2005 14:48:07 +0000

[...] Researchers at Imperial College London and the University of Liege, Belgium, used DNA microarrays to analyze 23 brains from recently deceased patients – 15 with Parkinson’s and 8 without. They screened 25,000 human genes and found that 570 were highly abnormal in Parkinsons brains. Now they’ll have to comb through the 570 genes and figure out which ones have significant functional roles in the etiology of Parkinson’s disease. Good luck! [...]

By: Hsien Hsien Lei, PhD

Hsien Hsien Lei, PhD — Sat, 10 Dec 2005 13:59:32 +0000

Thanks for your comment, Kobayashi. For a non-computer scientist like me, check-sum is plenty complicated enough! But I do agree that computer applications to genomic problems is going to be increasingly important as the amount of data grows exponentially.

By: Kobayashi

Kobayashi — Sat, 10 Dec 2005 12:49:33 +0000

I must say checksum is not a copmplicated method compared ones we study at computer science. When i read this post i realize that there are huge opornuties to work on genetics as computer engineer. But i must say, we learned check-sum in network lessons not related to E-Mail. This is new for me.

By: » E-Mail Technology Used to Analyze DNA Data Genetics and Health

» E-Mail Technology Used to Analyze DNA Data Genetics and Health — Fri, 09 Dec 2005 03:45:52 +0000

[...] Using the check-sum protocol, it’s possible to monitor more closely time-series data from DNA microarrays of genes turning on and off. Generally, when biological pathways such as cell division or immune system responses are being studied, there is some loss of information between sequential “snapshots” of the microarray. [...]