http://www.blisstree.com/articles/genetics-in-the-jewish-standard/ Family, Health, Home and Lifestyles Fri, 04 Dec 2009 21:12:15 -0500 http://wordpress.org/?v=2.8.4 hourly 1 http://www.blisstree.com/articles/genetics-in-the-jewish-standard/comment-page-1/#comment-567715 Hsien Hsien Lei, PhD Sat, 02 Dec 2006 10:51:20 +0000 http://www.geneticsandhealth.com/2006/11/24/genetics-in-the-jewish-standard/#comment-567715 <b>Emily</b>: While it's true that there are many possibly mutations within BRCA1 and 2 and other genes involved in breast and ovarian cancers, there are a few genetic variants that account for the majority of hereditary cases. No genetic test will ever be able to predict the risk of disease 100% of the time but any good genetic counselor will be able to give the patient a feel for how dependable the results are. Emily: While it’s true that there are many possibly mutations within BRCA1 and 2 and other genes involved in breast and ovarian cancers, there are a few genetic variants that account for the majority of hereditary cases. No genetic test will ever be able to predict the risk of disease 100% of the time but any good genetic counselor will be able to give the patient a feel for how dependable the results are.

]]> http://www.blisstree.com/articles/genetics-in-the-jewish-standard/comment-page-1/#comment-567709 Emily DeVoto Thu, 30 Nov 2006 17:06:28 +0000 http://www.geneticsandhealth.com/2006/11/24/genetics-in-the-jewish-standard/#comment-567709 Good stuff, Hsien. With regard to BRCA1 and 2, the discovery of all the different mutations has led us into extremely murky waters, as you know, and I think it goes beyond whether a direct-to-consumer genetic test is accompanied by professional counseling. It's no longer a question of BRCA positive vs. negative; now we have to make judgments about the significance of any of hundreds of mutations, not only in and of themselves but in the context of all of the other breast cancer risk factors we know about. I'm sure you're more up on this than I am; is it fair to say that the data we have on those individual mutations are just too thin to draw firm conclusions about risk? Good stuff, Hsien. With regard to BRCA1 and 2, the discovery of all the different mutations has led us into extremely murky waters, as you know, and I think it goes beyond whether a direct-to-consumer genetic test is accompanied by professional counseling. It’s no longer a question of BRCA positive vs. negative; now we have to make judgments about the significance of any of hundreds of mutations, not only in and of themselves but in the context of all of the other breast cancer risk factors we know about. I’m sure you’re more up on this than I am; is it fair to say that the data we have on those individual mutations are just too thin to draw firm conclusions about risk?

]]> http://www.blisstree.com/articles/genetics-in-the-jewish-standard/comment-page-1/#comment-567704 Genetics and Health » Response to Genetics Article in The Jewish Standard Wed, 29 Nov 2006 23:55:00 +0000 http://www.geneticsandhealth.com/2006/11/24/genetics-in-the-jewish-standard/#comment-567704 [...] In response to the series of genetics articles published in The Jewish Standard last week, I asked Lisa Lee of DNA Direct to share her thoughts specifically on the article about direct-to-consumer genetic testing by Dr. Miryam Wahrman. [...] [...] In response to the series of genetics articles published in The Jewish Standard last week, I asked Lisa Lee of DNA Direct to share her thoughts specifically on the article about direct-to-consumer genetic testing by Dr. Miryam Wahrman. [...]

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