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	<title>Comments on: How Do You Make a Rain Mouse?</title>
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		<title>By: Regan</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-548783</link>
		<dc:creator>Regan</dc:creator>
		<pubDate>Fri, 15 Feb 2008 22:48:53 +0000</pubDate>
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		<description>RAJ,
Thank you very much for taking the time to find the full text of the Kanner paper. Much appreciated. It&#039;s helpful to be able and put this into a historical framework.</description>
		<content:encoded><![CDATA[<p>RAJ,<br />
Thank you very much for taking the time to find the full text of the Kanner paper. Much appreciated. It&#8217;s helpful to be able and put this into a historical framework.</p>
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		<title>By: RAJ</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-541492</link>
		<dc:creator>RAJ</dc:creator>
		<pubDate>Fri, 15 Feb 2008 14:23:53 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-541492</guid>
		<description>Kristina wrote:

&quot;My son has never been diagnosed with mental retardation, though—based on his cognitive performance and school work and minimal language—I think this would have been his diagnosis in the past. 

No epidemic of autism, 1st or 2nd……&quot;

I agree with you that there is no epidemic of autism, neither in the early 1960&#039;s or after the introduction of DSM-III-R, ICD-10, ADOS-R, ARI-R and other &#039;Gold Standard&#039; instruments to diagnose an ASD. 

All of these Gold Standard diagnostic tools have included an ever expanding checklist of autistic &#039;symptoms&#039; in a Chinese menu fashion, one from column A, two from Column B...

The core problem is that isolated features which are a featured part of the overall syndrome of autism but are not specific to autism are all given equal weight under these diagnostic schemes and what Kanner called the &#039;sui generis&#039; of the core defining feature of autism has been lost, leading to the myth of the autism epidemic just as it did in the early 1960&#039;s.

The best evidence is the data produced by the Autism Genome Consortium this year alone. The entire concept of the Consortium is flawed, they look at only the minority of children with a specific genetic anomaly that meet criteria for an ASD, and cannot see (because of the design flaw) the majority of cases who do not meet the criteria for an ASD and are excluded from the studies leading to false assumptions and misleading conclusions.

Every single finding published this year (SHANK3, Neuroligins etc.) have all been previously reported in patient populations with a variety of neurological conditions, primarily mental retardation, but not autism. In every single case the Consortium has promoted as an &#039;autism&#039; gene, the phenotype is actually mental retardation with a minority presenting with enough nonspecific autistic features to qualify for an ASD diagnosis.</description>
		<content:encoded><![CDATA[<p>Kristina wrote:</p>
<p>&#8220;My son has never been diagnosed with mental retardation, though—based on his cognitive performance and school work and minimal language—I think this would have been his diagnosis in the past. </p>
<p>No epidemic of autism, 1st or 2nd……&#8221;</p>
<p>I agree with you that there is no epidemic of autism, neither in the early 1960&#8217;s or after the introduction of DSM-III-R, ICD-10, ADOS-R, ARI-R and other &#8216;Gold Standard&#8217; instruments to diagnose an ASD. </p>
<p>All of these Gold Standard diagnostic tools have included an ever expanding checklist of autistic &#8217;symptoms&#8217; in a Chinese menu fashion, one from column A, two from Column B&#8230;</p>
<p>The core problem is that isolated features which are a featured part of the overall syndrome of autism but are not specific to autism are all given equal weight under these diagnostic schemes and what Kanner called the &#8217;sui generis&#8217; of the core defining feature of autism has been lost, leading to the myth of the autism epidemic just as it did in the early 1960&#8217;s.</p>
<p>The best evidence is the data produced by the Autism Genome Consortium this year alone. The entire concept of the Consortium is flawed, they look at only the minority of children with a specific genetic anomaly that meet criteria for an ASD, and cannot see (because of the design flaw) the majority of cases who do not meet the criteria for an ASD and are excluded from the studies leading to false assumptions and misleading conclusions.</p>
<p>Every single finding published this year (SHANK3, Neuroligins etc.) have all been previously reported in patient populations with a variety of neurological conditions, primarily mental retardation, but not autism. In every single case the Consortium has promoted as an &#8216;autism&#8217; gene, the phenotype is actually mental retardation with a minority presenting with enough nonspecific autistic features to qualify for an ASD diagnosis.</p>
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		<title>By: RAJ</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-541237</link>
		<dc:creator>RAJ</dc:creator>
		<pubDate>Fri, 15 Feb 2008 14:05:20 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-541237</guid>
		<description>Regan;

Regarding your question about Leo Kanners observation about the over diagnosing of autism. The article was published in 1965 in Behavioral Science. I found the entire article on a website and am posting the link for you:

http://neurodiversity.com/library_kanner_1965.html


This sage advice was not heeded by many authors. While the majority of the Europeans were satisfied with a sharp delineation of infantile autism as an illness sui generis, there was a tendency in this country to view it as a developmental anomaly ascribed exclusively to maternal emotional determinants. Moreover, it became a habit to dilute the original concept of infantile autism by diagnosing it in many disparate conditions which show one or another isolated symptom found as a part feature of the overall syndrome. Almost overnight, the country seemed to be populated by a multitude of autistic children, and somehow this trend became noticeable overseas as well. Mentally defective children who displayed bizarre behavior were promptly labeled autistic and, in accordance with preconceived notions, both parents were urged to undergo protracted psychotherapy in addition to treatment directed toward the defective child&#039;s own supposedly underlying emotional problem.</description>
		<content:encoded><![CDATA[<p>Regan;</p>
<p>Regarding your question about Leo Kanners observation about the over diagnosing of autism. The article was published in 1965 in Behavioral Science. I found the entire article on a website and am posting the link for you:</p>
<p><a href="http://neurodiversity.com/library_kanner_1965.html" rel="nofollow">http://neurodiversity.com/library_kanner_1965.html</a></p>
<p>This sage advice was not heeded by many authors. While the majority of the Europeans were satisfied with a sharp delineation of infantile autism as an illness sui generis, there was a tendency in this country to view it as a developmental anomaly ascribed exclusively to maternal emotional determinants. Moreover, it became a habit to dilute the original concept of infantile autism by diagnosing it in many disparate conditions which show one or another isolated symptom found as a part feature of the overall syndrome. Almost overnight, the country seemed to be populated by a multitude of autistic children, and somehow this trend became noticeable overseas as well. Mentally defective children who displayed bizarre behavior were promptly labeled autistic and, in accordance with preconceived notions, both parents were urged to undergo protracted psychotherapy in addition to treatment directed toward the defective child&#8217;s own supposedly underlying emotional problem.</p>
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		<title>By: Marla</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-541631</link>
		<dc:creator>Marla</dc:creator>
		<pubDate>Fri, 15 Feb 2008 02:39:02 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-541631</guid>
		<description>Interesting stuff.</description>
		<content:encoded><![CDATA[<p>Interesting stuff.</p>
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		<title>By: daedalus2u</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-541716</link>
		<dc:creator>daedalus2u</dc:creator>
		<pubDate>Thu, 14 Feb 2008 20:30:57 +0000</pubDate>
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		<description>I agree with Ms Clark.  This bears little even superficial resemblance to autism or savant abilities.  I see it as funding motivated analogies.</description>
		<content:encoded><![CDATA[<p>I agree with Ms Clark.  This bears little even superficial resemblance to autism or savant abilities.  I see it as funding motivated analogies.</p>
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		<title>By: Regan</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-546709</link>
		<dc:creator>Regan</dc:creator>
		<pubDate>Thu, 14 Feb 2008 20:06:54 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-546709</guid>
		<description>&quot;In 1965 Leo Kanner, the clinician who first recognized autism as a distinct neuropsychiatric disorder voiced his objection to the 1960’s ‘epidemic’ of autism when mentally retarded children with bizarre behaviors who shared one or more part features of the syndrome of autism were given the fashionable label of ‘autism’.&quot;

RAJ, you&#039;ve mentioned that a couple of times. I&#039;m intrigued; where could I find/what&#039;s the citation for that? I&#039;d like to read it first-hand. Thanks.</description>
		<content:encoded><![CDATA[<p>&#8220;In 1965 Leo Kanner, the clinician who first recognized autism as a distinct neuropsychiatric disorder voiced his objection to the 1960’s ‘epidemic’ of autism when mentally retarded children with bizarre behaviors who shared one or more part features of the syndrome of autism were given the fashionable label of ‘autism’.&#8221;</p>
<p>RAJ, you&#8217;ve mentioned that a couple of times. I&#8217;m intrigued; where could I find/what&#8217;s the citation for that? I&#8217;d like to read it first-hand. Thanks.</p>
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		<title>By: Ms. Clark</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-551327</link>
		<dc:creator>Ms. Clark</dc:creator>
		<pubDate>Thu, 14 Feb 2008 19:18:04 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-551327</guid>
		<description>The thing that makes savants savants is their prodigious long term memories.  One explanation behind their ability to do calendar calculating is that they look at calendars over an extended period of time and absorb or learn or whatever the pattern so that they can apply it to future and past dates.  

Savants who learn to play music don&#039;t forget songs that they learn.  Savants that memorize stuff don&#039;t turn around and forget it all, if they did why would anyone ever make a fuss over their skill?  

These mice look more like a mouse model for amnesia.  But typically, anyone who thinks they have a thing that can get funded as autism research will bend it that way because whereas there&#039;s little money for &quot;amnesia&quot; research there&#039;s plenty for autism research because of all the bizarros howling about a fake autism epidemic.</description>
		<content:encoded><![CDATA[<p>The thing that makes savants savants is their prodigious long term memories.  One explanation behind their ability to do calendar calculating is that they look at calendars over an extended period of time and absorb or learn or whatever the pattern so that they can apply it to future and past dates.  </p>
<p>Savants who learn to play music don&#8217;t forget songs that they learn.  Savants that memorize stuff don&#8217;t turn around and forget it all, if they did why would anyone ever make a fuss over their skill?  </p>
<p>These mice look more like a mouse model for amnesia.  But typically, anyone who thinks they have a thing that can get funded as autism research will bend it that way because whereas there&#8217;s little money for &#8220;amnesia&#8221; research there&#8217;s plenty for autism research because of all the bizarros howling about a fake autism epidemic.</p>
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		<title>By: Kristina Chew, PhD</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-541761</link>
		<dc:creator>Kristina Chew, PhD</dc:creator>
		<pubDate>Thu, 14 Feb 2008 18:42:36 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-541761</guid>
		<description>My son has never been diagnosed with mental retardation, though---based on his cognitive performance and school work and minimal language---I think this would have been his diagnosis in the past. 

No epidemic of autism, 1st or 2nd......</description>
		<content:encoded><![CDATA[<p>My son has never been diagnosed with mental retardation, though&#8212;based on his cognitive performance and school work and minimal language&#8212;I think this would have been his diagnosis in the past. </p>
<p>No epidemic of autism, 1st or 2nd&#8230;&#8230;</p>
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		<title>By: RAJ</title>
		<link>http://www.blisstree.com/articles/how-do-you-make-a-rain-mouse/comment-page-1/#comment-551291</link>
		<dc:creator>RAJ</dc:creator>
		<pubDate>Thu, 14 Feb 2008 18:31:22 +0000</pubDate>
		<guid isPermaLink="false">http://www.autismvox.com/how-do-you-make-a-rain-mouse/#comment-551291</guid>
		<description>SHANK3 defects have been found in ASD subjects but also in people with mental retardation without an ASD diagnosis. The failure of genetic research in autism is its inability to control for the confounding variable of mental retardation associated with autism type features.

http://www.ncbi.nlm.nih.gov/pubmed/16284256?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

In 1965 Leo Kanner, the clinician who first recognized autism as a distinct neuropsychiatric disorder voiced his objection to the 1960&#039;s &#039;epidemic&#039; of autism when mentally retarded children with bizarre behaviors who shared one or more part features of the syndrome of autism were given the fashionable label of &#039;autism&#039;.

The current vastly expanded definition and criteria used to confer a diagnosis are vague, ambigous and subjective. This likely explains the second autism epidemic and also explains why such diverse children as Fragile X mentally retarded boys, brain damaged children, language delayed children people with personality disorders and even Romanian orphans who were institutionalized as infants and suffered severe emotional deprivation, abuse and neglect can all meet diagnostic criteria for an ASD.</description>
		<content:encoded><![CDATA[<p>SHANK3 defects have been found in ASD subjects but also in people with mental retardation without an ASD diagnosis. The failure of genetic research in autism is its inability to control for the confounding variable of mental retardation associated with autism type features.</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/16284256?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/16284256?ordinalpos=2&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum</a></p>
<p>In 1965 Leo Kanner, the clinician who first recognized autism as a distinct neuropsychiatric disorder voiced his objection to the 1960&#8217;s &#8216;epidemic&#8217; of autism when mentally retarded children with bizarre behaviors who shared one or more part features of the syndrome of autism were given the fashionable label of &#8216;autism&#8217;.</p>
<p>The current vastly expanded definition and criteria used to confer a diagnosis are vague, ambigous and subjective. This likely explains the second autism epidemic and also explains why such diverse children as Fragile X mentally retarded boys, brain damaged children, language delayed children people with personality disorders and even Romanian orphans who were institutionalized as infants and suffered severe emotional deprivation, abuse and neglect can all meet diagnostic criteria for an ASD.</p>
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