Comments on: Large family with restless leg syndrome may have novel gene http://www.blisstree.com/articles/large-family-with-restless-leg-syndrome-may-have-novel-gene/ Family, Health, Home and Lifestyles Thu, 17 Dec 2009 07:22:36 -0500 http://wordpress.org/?v=2.8.4 hourly 1 By: Mysteries of Restless Legs Syndrome : Blisstree - Family, Health, Home and Lifestyles http://www.blisstree.com/articles/large-family-with-restless-leg-syndrome-may-have-novel-gene/comment-page-1/#comment-574957 Mysteries of Restless Legs Syndrome : Blisstree - Family, Health, Home and Lifestyles Mon, 02 Nov 2009 21:08:35 +0000 http://www.geneticsandhealth.com/2009/02/05/large-family-with-restless-leg-syndrome-may-have-novel-gene/#comment-574957 [...] one really knows what causes restless legs syndrome (RLS). People who have this problem experience a strong urge to move their legs when they should be [...] [...] one really knows what causes restless legs syndrome (RLS). People who have this problem experience a strong urge to move their legs when they should be [...]

]]> By: Jessica http://www.blisstree.com/articles/large-family-with-restless-leg-syndrome-may-have-novel-gene/comment-page-1/#comment-570318 Jessica Thu, 05 Feb 2009 16:23:52 +0000 http://www.geneticsandhealth.com/2009/02/05/large-family-with-restless-leg-syndrome-may-have-novel-gene/#comment-570318 Um, the title you chose here is very misleading. The family does not have a potentially "novel gene" -- they may have a mutation at a novel LOCUS. A "novel gene" implies that there is a gene in the human genome that scientists have not yet discovered. The actual situation is that the Mayo scientists think that the family is transmitting a mutation at a novel locus (i.e. the gene is almost certainly known to science--it just hasn't been linked to RLS yet). There's a huge difference. Um, the title you chose here is very misleading. The family does not have a potentially “novel gene” — they may have a mutation at a novel LOCUS.

A “novel gene” implies that there is a gene in the human genome that scientists have not yet discovered. The actual situation is that the Mayo scientists think that the family is transmitting a mutation at a novel locus (i.e. the gene is almost certainly known to science–it just hasn’t been linked to RLS yet).

There’s a huge difference.

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