http://www.blisstree.com/articles/neuroligin-mutations-as-a-cause-of-autism/ Family, Health, Home and Lifestyles Sat, 12 Dec 2009 06:30:43 -0500 http://wordpress.org/?v=2.8.4 hourly 1 http://www.blisstree.com/articles/neuroligin-mutations-as-a-cause-of-autism/comment-page-1/#comment-543913 Of Mice, Synapses, and Autism Sun, 09 Dec 2007 18:26:58 +0000 http://www.autismvox.com/neuroligin-mutations-as-a-cause-of-autism/#comment-543913 [...] a normal mouse neurologin-3 gene with a mutated neuroligin-3 gene associated with autism in humans.Neurologins ensure that signal transitions between nerve cells function and are “expressed on the surface of [...] [...] a normal mouse neurologin-3 gene with a mutated neuroligin-3 gene associated with autism in humans.Neurologins ensure that signal transitions between nerve cells function and are “expressed on the surface of [...]

]]> http://www.blisstree.com/articles/neuroligin-mutations-as-a-cause-of-autism/comment-page-1/#comment-531094 Autism Vox » New Study on the Genetic Causes of Autism Sun, 18 Feb 2007 18:40:43 +0000 http://www.autismvox.com/neuroligin-mutations-as-a-cause-of-autism/#comment-531094 [...] Neurexins are “a large family of proteins that act as neuronal cell-surface receptors” (Nature Neuroscience 6, 708 - 716 (2003); they and neuroligins have been implicated as having a role in autism. The Nature Genetics study pinpoints neurexin-neuroligin link as “fundamentally important for glutamatergic synaptogenesis and thereby points to “glutamate-related genes as promising candidates for contributing to ASDs.” (Glutamate is a common excitatory neurotransmitter in the central nervous system and plays a crucial role in both memory formation and information processing; “synaptogenesis” refers to the formation of synapses.) [...] [...] Neurexins are “a large family of proteins that act as neuronal cell-surface receptors” (Nature Neuroscience 6, 708 – 716 (2003); they and neuroligins have been implicated as having a role in autism. The Nature Genetics study pinpoints neurexin-neuroligin link as “fundamentally important for glutamatergic synaptogenesis and thereby points to “glutamate-related genes as promising candidates for contributing to ASDs.” (Glutamate is a common excitatory neurotransmitter in the central nervous system and plays a crucial role in both memory formation and information processing; “synaptogenesis” refers to the formation of synapses.) [...]

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