Sorafenib: Miracle Pill for Liver Cancer
June 5, 2007 by Gloria Gamat
Filed under Diseases & Conditions
Presented Monday at the annual meeting of the American Society of Clinical Oncology, the cure for liver cancer in Sorafenib.
Phase III clinical trial data of this miracle pill revealed that chances of survival from final stage liver cancer is increased by 44% or about three months life extension.
Final stage liver cancer is deadly and currently patients suffering this condition have no treatment option.
Sorafenib is a pill that directly targets malignant cancer cells and cuts off the blood supply feeding the tumour and has been found in a large scale multinational trial, conducted by researchers from the Mount Sinai School of Medicine in New York and Hospital Clinic of Barcelona (Spain), to work on tumors within the liver and those that have already spread in other parts of the body.
According to Dr Subhash Gupta, head of department, liver surgery, Apollo Hospital:
“Sorafenib holds great promise for patients on whom aggressive options like a mix of surgery, radiation and chemotherapy fail.
Once detected early, liver cancer can be addressed by either a transplant or other techniques.”
Sorafenib is co-marketed by Bayer Healthcare Pharmaceuticals and Onyx Pharmaceuticals as Nexavar® - which is already indicated for the treatment of advanced renal cell carcinoma (kidney cancer).
Find more details from the full report at India Times and Science Daily.
The extra days are for the “group” in the study, not the “individual” patients treated in the real world. This affirms that in the tactic of using “fresh” biopsied cells to predict which cancer treatments will work best for the patient, this “smart” drug has to get inside the cells in order to “target” anything. If the drug either won’t “get in” in the first place or if it gets pumped out/extruded or if it gets immediately metabolized inside the cell, it just isn’t going to work. Each of these new “targeted” drugs are not for everybody. Even when the disease is the same type, different patients’ tumors respond differently to the same agent. If a drug works extremely well for a certain percentage of cancer patients, identify which ones. If one drug or another is working for some people (not average populations) then obviously there are others out there who would also benefit.
is sorafenib available in the UK ?
alex: according to this BBC news, Nexavar (sorafenib) is available in some part of england.
http://news.bbc.co.uk/1/hi/wales/north_east/6638053.stm
remember though that this is a prescription drug.
Does anyone know if sorafenib is approved for HCC patients in Australia?
My mother is suffering from liver cancer. she is in 4th last stage.
Can you give any suggestion to save her life.
I wish to save my uncle from liver cancer.I tried to purchase Sorafenib tablets in the state of Tamil Nadu,India but to no avail.Even the leading Pharamacy are seeking time,but I require it very very urgently.Can anybody help me in locating Sorafenib tablets for immediate purchase in India.Thank You.
Can anyone advise where can I buy Soafenib in Europe. My father is having now chemiotherapy, Sorafenib could possibly help as well. I live in Poland, but I could go to the state where it is available or ask friends to buy.
Thanks.
Sorafenib tablets as available in bombay , if anyone is looking for one , and yes they are also available in boots in UK
please tell me where i can get the tablet sorafenib for my father who is detected with liver tumor.
Manish , tell me which part of india r u frm,
mail me and i will let you knw where is it
rgds
Hello Rajesh. You mentioned we can get sorafenib in Bombay. I need it for my mother in law. Can you tell me where I can get it, or how can I email you (as you mention).
Manoj
if you need more details mail me on rlkanojia@gmail.com or rajesh@shikharlogistics.com
Does anyone know if sorafenib is availaible in Indonesia? My mother now in chemotherapy, she’s detected liver cancer almost one year ago
My Sister has been diagnosed with Pancreatic Cancer , spread to Liver i.e Liver mets. She had two doses of Chemo, Gemcitabine. What bnest we can do to save her life. Please help.
Ramesh – Where is your Sister located?
Hi
my father is diagnosed with liver cancer very recently,he is living in sri lnka,so could you please let me know that “SORAFENIB” is available in sri lanka Thanks. Pradeep.deepden6@hotmail.com
i have a patient with liver cancer who was prescribed sorafenib
in sri lanka. pl tell me the details a way of purchasing it cheaply
from sri lanka or abroad
thanks
Pradeep,
Sorry to hear that your father is diagnosed with this. Mine was just too and I am looking for treatment options. Please can you let me know if you were able to find the drug in Sri Lanka and how effective it was. Hope your father’s condition is improving.
Thanks
Sumeda
I have 1 box (60 tablets) Nexavar/ Sorafenib, I want to share with anyone who need it, my mom consume it for her liver cancer too and I buy several box from the supplier (Bayer). I live in Jakarta, Indonesia. Please email to erliana_er@yahoo. com if u need the mediceine. Thanks!
hi! how is your mom now? my mom also is having malignant liver cancer. She was diagnosed last January 2009. She is only taking vitamins and all but refused to undergo chemotheraphy, for she believes it will only kill her than the cancer itself. Is your mom reacting to this Sorafenib pill positively? Please let me know… Thanks and best regards.
how can i get sorafenib in malaysia?anyone can help me?
My father has a liver cancer who was prescribed sorafenib
in sri lanka. pl tell me the details a way of purchasing it cheaply
from sri lanka or abroad
thanks
My father is suffering from advance liver cancer. Please let me know where I can Purchase Sorafenib in Sri Lanka.
Hi,
Sorry to hear that your father is diagnosed with cancer. Mine was just too and I am looking for treatment options. Please can you let me know if you were able to find the drug in Sri Lanka and how effective it was. Hope your father’s condition is improving.
Thanks
Sumeda
Hi,
My father is in a real advanced stage of liver cancer. He is almost bedridden. He has diffuclty in eating. his both legs are swollen. allopathic doctor has already told that the chances of his survival are nil. Can anyone help me at this stage pls. This is urgent.
Regards
Praful Maru