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Genetically screening patients before they have antibiotics may prevent hearing loss

October 27, 2007 by Elaine  
Filed under Health

Genetically screening patients before they have antibiotics may prevent hearing loss

Some patients, particularly young children, may be born with a genetic mutation which means they are at risk of hearing loss after taken antibiotics called aminoglycosides.  There is now a drive to consider screening patients for the genetic mutation known as m.1555A-G which is held in around 1 in 1,611 newborns in the USA, 1 in 206 newborns in New Zealand and 1 in 40,000 newborns in the UK.
Aminoglycosides are valuable antibiotics used for serious infections such as complicated urinary tract infections, TB and septicemia.  They are known to potentially cause damage to the ear – otoxicity. Individuals holding the mutation have an …read more


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