Blisstree » avandia http://www.blisstree.com Family, Health, Home and Lifestyles Fri, 18 Dec 2009 08:24:27 +0000 http://wordpress.org/?v=2.8.4 en hourly 1 Avandia, Diabetes Drug, May Cause Problems http://www.blisstree.com/articles/avandia-diabetes-drug-may-cause-problems/ http://www.blisstree.com/articles/avandia-diabetes-drug-may-cause-problems/#comments Wed, 19 Aug 2009 12:54:58 +0000 Marijke Durning, RN http://www.blisstree.com/?p=106531 Post from: Blisstree

Avandia, Diabetes Drug, May Cause Problems

]]> Avandia (rosiglitazone), a medication for people with type 2 diabetes, has been the subject of studies evaluating its safety and the results aren’t what Glaxo (the manufacturer) had hoped for. According to researchers in Toronto, Canada, elderly people who take Avandia may have an increased risk of heart failure and death.

xchng_happy_elderly_coupleThe researchers didn’t, however, find the same results that American researchers found two years earlier, which suggested that Avandia also increased the risk of heart attacks. The Canadian researchers found no difference between patients who took Avandia and another type of medication, Actos (pioglitazone), and the rate of heart attacks among them

The researchers studied 40,000 patients over the age of 65 who took Avandia or Actos. For every 93 patients, there was one more heart “event” or death each year among those who took Avandia.

This being said, this doesn’t mean that Avandia shouldn’t be used to treat type 2 diabetes. The results show that perhaps it shouldn’t be prescribed for people who are in high risk groups or who have heart disease already.

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Photo: StockXchng.com

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Avandia, Diabetes Drug, May Cause Problems

]]> http://www.blisstree.com/articles/avandia-diabetes-drug-may-cause-problems/feed/ 1 Actos and Avandia being linked to increased heart failure http://www.blisstree.com/articles/actos-and-avandia-being-linked-to-increased-heart-failure-50/ http://www.blisstree.com/articles/actos-and-avandia-being-linked-to-increased-heart-failure-50/#comments Fri, 29 Aug 2008 16:03:53 +0000 Kendra James, RN http://www.aheartylife.com/2008/08/29/actos-and-avandia-being-linked-to-increased-heart-failure/ Post from: Blisstree

Actos and Avandia being linked to increased heart failure

]]> Over 20% of all diabetics have heart disease. That is why it is so scary when new research and studies come out that prove diabetic medication to harm your heart. And here we go again… Two Wake Forest University School of Medicine faculty members sifted through three trials to come to the conclusion that certain diabetic medications could cause increased heart failure- ACCORD, ADVANCE, and the Veterans Affairs Diabetes study.

“We strongly recommend restrictions in the use of thiazolidinediones (the class of drugs) and question the rationale for leaving rosiglitazone on the market,” write Sonal Singh, M.D., M.P.H., assistant professor of internal medicine, and Curt D. Furberg, M.D., Ph.D., professor of public health sciences. Rosiglitazone and pioglitazone are the two major thiazolidinediones.

What are the drugs being above mentioned? Actos and Avandia. If you take these medications please talk to your physician if you have any concerns or questions.  Remember, you need the risk factors to be affected in a negative way.

via Wake Forest 

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Actos and Avandia being linked to increased heart failure

]]> http://www.blisstree.com/articles/actos-and-avandia-being-linked-to-increased-heart-failure-50/feed/ 0 FDA Gives Avandia The OK To Stay On The Market http://www.blisstree.com/articles/fda-gives-avandia-the-ok-to-stay-on-the-market-50/ http://www.blisstree.com/articles/fda-gives-avandia-the-ok-to-stay-on-the-market-50/#comments Mon, 30 Jul 2007 23:29:03 +0000 Kendra James, RN http://www.aheartylife.com/2007/07/31/fda-gives-avandia-the-ok-to-stay-on-the-market/ Post from: Blisstree

FDA Gives Avandia The OK To Stay On The Market

]]> I posted this as well over at Diabetes Notes, but I think it is big enough news that you will excuse the duplication.

Ok, it is official… Avandia will stay on the market.  The FDA voted an overwhelming yes to keeping the drug on the shelves.  They stated that they are recommending that there be warning labels for the elder population and high risk cardiac patients. 

And as you can guess, this is getting a bag of mixed emotions.  Will this stop the 1000’s of lawsuits that are currently existing due to Avandia’s heart implications?  I think not.  But it will give the pharmaceutical company more than a leg to stand on.

It is estimated that Avandia was responsible for contributing to 80,000 heart attacks over the last 8 years.  Can they point the finger solely at Avandia?  Were there pre-existing factors?  Who is to say, I will leave that one to the attorneys and such. 

It is a bit like the Vioxx scare a few years back.  Did all orthopedics stop prescribing this medication after the cardiac warnings and accusations came out?  Nope, not even close.  Heck, my orthopod even uses it himself.  But there were tons, and I mean tons, of money awarded in the courts. 

Time will tell how much of an effect the FDA approval has on the already suffering Avandia.  Will it bounce back?  I know that personally while I was at the doctor’s office this morning, the drug rep came skipping in pushing the use of Avandia and proclaiming it’s innocence.  What do you think?  Do you still take Avandia?  Do you have a heart condition?  Will you stay on the medicine?  So many questions, so little time! 

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FDA Gives Avandia The OK To Stay On The Market

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