Biomarkers for Ovarian Cancer, Identified
March 13, 2007 by Gloria Gamat
Filed under Diseases & Conditions
A team of researchers from the University of Michigan, University of Pennsylvania, and universities in Greece and Italy have been able ton identify biomarkers unique the cells of blood vessels running through ovarian tumors.
According to study author Ronald Buckanovich, M.D., Ph.D., assistant professor of internal medicine and obstetrics and gynecology at the University of Michigan Medical School:
“Some of these genes, depending on how highly expressed they were in the tumor vasculature, were also prognostic of a patient’s survival.
We suspect when these genes are highly expressed it may be a sign of a tumor that’s able to grow blood vessels more …read more
Growth Factor Protein Proepithelin: Biomarker for Bladder Cancer, Potential Drug Target
July 28, 2006 by Gloria Gamat
Filed under Diseases & Conditions
Scientists at Jefferson Medical College and Jefferson’s Kimmel Cancer Center probably have identified a potential target for drugs by demonstrating that a growth factor protein called proepithelin plays a crucial role in the spread of bladder cancer.
Because proepithelin seem not to strongly promoter cell proliferation but instead promotes migration and invasion (two crucial steps leading to metastasis) then it could be could be critical for the passage of a cancer from a noninvasive to an invasive phenotype.
Andrea Morrione, Ph.D. (research assistant professor of urology), Jefferson Medical College of Thomas Jefferson University and Jefferson’s Kimmel Cancer Center in Philadelphia, heading the …read more




