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Wednesday, December 2nd, 2009

Grapefruit and Orange Flavonoid Prevents Cancer by Repairing DNA

February 6, 2007 by ruth  
Filed under Recipes

Grapefruit and Orange Flavonoid Prevents Cancer by Repairing DNA

A study published in the Journal of Nutritional Biochemistry reports that naringenin, a flavonoid compound found in grapefruit and oranges may help prevent cancer, and not just because of its antioxidant properties. Apparently naringenin induced DNA repair in human prostate cancer cell cultures (cell line LNCaP).
The degree of repair was measured by the ratio between deoxyguanosine (dG) and 8-hydroxydeoxyguanosine (8-OH-dG). The former is found in normal DNA, while the latter is the product of hydroxyl radical attack – found in damaged DNA.
After 24 hours of exposure to 80 micromoles per liter of naringenin, the ratio of 8 -OH-dG to dG …read more


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