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Thursday, November 12th, 2009

Statins Might Protect Against Alzheimer’s

June 23, 2009 by Peggy Rowland  
Filed under Women's Health

Statins Might Protect Against Alzheimer’s

Do you take statins? If so, you could also be fighting off Alzheimer’s disease.
Researchers in The Netherlands showed that statins, normally taken to lower bad cholesterol, can also protect nerve cells from becoming damaged, as occurs in the brain of people with Alzheimer’s disease.
That nerve cell protection is believed to lower the risk of developing Alzheimer’s disease. According to Alzheimer’s Association, as many as 5.3 million people in the US live with the disease.

In animal experiments conducted in the lab at University of Groningen, the statin Lovastatin prevented nerve cells from dying and thereby prevented the loss of memory capacity.
The …read more

Lovastatin- Cyclopamine Combo Kills Brain Cancer Cells

January 22, 2007 by Gloria Gamat  
Filed under Diseases & Conditions

Lovastatin- Cyclopamine Combo Kills Brain Cancer Cells

Lovastatin (trade name: Mevacor) is a cholesterol lowering drug while cyclopamine is a cancer drug.
Cyclopamine works by blocking the so-called “hedgehog” pathway, long known to promote and guide cell and organ growth while lovastatin (aside from cholesterol-clogging effects) is known to curb destruction of proteins that put the brakes on cell growth, causing cancer cells to self-destruct through a process called apoptosis.
The unlikely pair of these two compounds has been found by researchers at the Johns Hopkins Kimmel Cancer Center to dramatically kill brain cancer cells.
Once the hedgehog is blocked by cyclopamine, the cancer cells become more susceptible to lovastatin.
The …read more


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