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Measles Virus: A Tool Against Multiple Myeloma?

March 8, 2007 by Gloria Gamat  
Filed under Diseases & Conditions

Measles Virus: A Tool Against Multiple Myeloma?

Multiple myeloma is a cancer of the bone that currently has no cure.
In a new phase I clinical trial opened by Mayo Clinic Cancer Center, a bioengineered measles virus is being tested of its potential to kill cancer.
This the third of a series of molecular medicine studies in patients testing the potential of measles to kill cancer. Previous studies were on glioblastoma multiforme (a brain tumor) and recurrent ovarian cancer.
Many cancers, including multiple myeloma, overexpress a protein, CD46, which allows them to evade destruction by the immune system. Laboratory strains of measles virus seek out this protein and use it as …read more


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