Multiple myeloma is a cancer of the bone that currently has no cure.
In a new phase I clinical trial opened by Mayo Clinic Cancer Center, a bioengineered measles virus is being tested of its potential to kill cancer.
This the third of a series of molecular medicine studies in patients testing the potential of measles to kill cancer. Previous studies were on glioblastoma multiforme (a brain tumor) and recurrent ovarian cancer.
Many cancers, including multiple myeloma, overexpress a protein, CD46, which allows them to evade destruction by the immune system. Laboratory strains of measles virus seek out this protein and use it as …read more

In a phase II trial led by a University of North Carolina at Chapel Hill School of Medicine researcher found that a newly formulated chemotherapy drug Doxil (doxorubicin delivered via liposomes, or microscopic fat bubbles) combined with standard therapy Velcade slows the progression of multiple myeloma better than Velcade alone.
Multiple myeloma is an advanced cancer of the bone marrow cells.
An interim analysis of study participants who received the combination treatment showed a better response in the combination group than in participants who received standard treatment.
The combination group’s median time to progression – the time interval between the response to treatment …read more

Multiple myeloma (MM) is the overgrowth of abnormal cells in the bone marrow leading to the painful destruction of the bone.Multiple myeloma has no known cure and diagnosis of such a condition means a watch and wait approach: high-dose chemotherapy followed by repeated treatments with each relapse of the cancer.
Phew…I cringe by just the thought…
However, a team of international researchers from France, Switzerland, and Belgium have explored a new approach of providing patients with continuous therapy to keep this kind of cancer at bay.
In this study, pamidronate, a drug often used early in the treatment of multiple myeloma to help protect against …read more