Mutations in a gene called FIGLA cause premature ovarian failure in at least 1% of women who suffer from the disorder, said researchers from Baylor College of Medicine in Houston and Shandong University in China in a report that appears online in the American Journal of Human Genetics. Premature ovarian failure, which means that the ovaries lose function before age 40, not only causes infertility but also bone and heart problems.  Ovarian reserves are important for women’s health.
FIGLA is one of four transcription factors found to control the differentiation of egg cells early in development. Transcription factors govern the activity of …read more