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New Chemoprevention Gene Therapy (CGT) Combo Kills Pancreatic Cancer Cells

August 6, 2008 by Gloria Gamat  
Filed under Diseases & Conditions

New Chemoprevention Gene Therapy (CGT) Combo Kills Pancreatic Cancer Cells

A research team from Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have showed that combining a dietary agent with a gene-delivered cytokine effectively eliminates human pancreatic cancer cells in mice displaying sensitivity to these highly aggressive and lethal cancer cells.
The cytokine used in this study was melanoma differentiation associated gene-7/interleukin-24, known as mda-7/IL-24.
The dietary agent, perillyl alcohol (POH), was combined with mda-7/IL-24, which is already used in other cancer treatments. POH is found in a variety of plants, including citrus plants, and has been well-tolerated by patients who have received it in clinical …read more


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