Polyunsaturated fatty acids (PUFA), especially those of the omega-3 series (EPA and DHA from fish), are known for their anti-inflammatory activity. This effect is important for the prevention/treatment of various chronic diseases such as cardiovascular disease or rheumatoid arthritis. The latest paper by the group of Francesco Visioli (Universite “Pierre et Marie Curie”, Paris) now adds a new piece to the puzzle of how PUFA exert their beneficial activity in the cardiovascular system: by lowering the load of potentially deleterious oxidative and nitrosative stress.
“In conclusion, based on in vivo data showing reduced excretion of lipid peroxidation products, namely isoprostanes, after …read more