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TRAIL + Sorafenib: New Combination for Cancer Cell Death

July 18, 2007 by Gloria Gamat  
Filed under Diseases & Conditions

TRAIL + Sorafenib: New Combination for Cancer Cell Death

A combination of TRAIL (a tumor necrosis factor) and sorafenib (an inhibitor currently used to treat renal cancer) has been found to reduce the size of tumors in mice with colon carcinomas with few side effects – thereby demonstrating the potential effectiveness of the combined treatment on human colon cancers.
Such were the new combination therapy identified by the University of Pennsylvania School of Medicine researchers.
According to Wafik S. El-Deiry, MD, PhD, professor of Medicine, Genetics, and Pharmacology:
“Cancer cells will do whatever it takes to survive in harsh environments. Our findings are exciting because TRAIL in combination with sorafenib appears to …read more


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