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Breast Cancer, Tamoxifen, and the CYP2D6 Gene

October 20, 2006 by Lei  
Filed under Health

Breast Cancer, Tamoxifen, and the CYP2D6 Gene

Big news for breast cancer patients on tamoxifen. Ryan Phelan and Jason Bobe of DNA Direct were at the FDA meeting on October 18th where it was decided that information about the cytochrome P450*2D6 (CYP2D6) gene should be included on the package insert and drug label.
From DNA Direct affiliate company Genes and Drugs:
The 2D6 gene is involved in the metabolism of many drugs, including some over-the-counter medications. Different people have different variations of this gene. Some variations metabolize 2D6 drugs very quickly, while others don’t metabolize them as well. Still others don’t metabolize them at all. Knowing your genetic status …read more


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